Do your legs swell with MS?
People who have MS sometimes have swollen legs. This leg swelling can occur for a number of reasons, particularly if it has become difficult to walk. In these circumstances, excess water may build up in the tissues and cause the legs to become swollen. Does MS cause fluid retention? Swollen feet and ankles are common in MS, and are caused by an accumulation of lymphatic fluid (lymphedema). They are considered to be a secondary symptom of the disease, because they most often develop due to a lack of mobility instead of arising as a direct result of demyelination.