Is Pseudohypoparathyroidism same as secondary hyperparathyroidism?
Some of the biochemical features of secondary hyperparathyroidism (e.g., hypocalcemia, elevated serum PTH) can also be seen in pseudohypoparathyroidism, a syndrome of resistance to the biochemical actions of PTH. What is the difference between hypoparathyroidism and pseudohypoparathyroidism? Two mechanisms may alter its function, limiting its control on calcium: insufficient PTH production by the parathyroids (hypoparathyroidism), or a resistance against its action in target tissues (pseudohypoparathyroidism). What is hypoparathyroidism pseudohypoparathyroidism? Pseudohypoparathyroidism. Several clinical disorders characterized by end-organ resistance to PTH have been described collectively by the term pseudohypoparathyroidism (PHP) (134-137).