What is evidence of prior granulomatous disease?
A persistent runny nose. Skin irritation that may include a rash, swelling or redness. Swelling and redness in your mouth. Gastrointestinal problems that may include vomiting, diarrhea, stomach pain, bloody stool or a painful pocket of pus near the anus. How do you get granulomatous disease? Chronic granulomatous disease is a genetic disorder and is caused by inherited defects in an important enzyme in white blood cells that manufactures oxidants for microbial killing.